Peer-Reviewed Evidence

    Clinical Evidence

    Published research demonstrates that robotic-assisted knee surgery with CORI technology delivers measurably better outcomes than conventional techniques—backed by rigorous clinical studies and real-world data.

    99.2%

    Implant Survivorship

    at 2 years post-surgery

    91%

    Alignment Accuracy

    within 1° of surgical plan

    >50%

    Faster Return to Sports

    4.2 vs 10.5 months

    24hrs

    Possible Discharge

    with appropriate selection

    Understanding the Challenge

    Why Precision Matters

    Conventional knee replacement is a successful intervention, but research shows significant room for improvement in patient outcomes.

    Over 50%

    of patients report some degree of limitation to their functional ability following conventional TKA

    Up to 20%

    of patients are not satisfied with their conventional total knee replacement

    Up to 60%

    of conventional UKA procedures result in alignment outliers beyond 2° of the planned position

    The evidence is clear: implant positioning significantly affects outcomes. Even small deviations from optimal alignment can impact how natural your knee feels, how long the implant lasts, and your overall satisfaction. This is why robotic-assisted surgery—with its sub-millimeter precision—represents such an important advancement.

    Published Research

    Evidence-Based Benefits

    Clinical studies consistently demonstrate advantages of robotic-assisted surgery across multiple outcome measures.

    Superior Implant Positioning

    • Significantly lower mechanical axis deviation (p=0.019)
    • Mean difference in planned vs achieved alignment: 0.2°
    • 91% of procedures achieve alignment within 1° of plan

    Source: Vaidya et al. 2020, Randomized Controlled Trial

    Improved Joint Line Restoration

    • Significantly improved joint line restoration (p<0.05)
    • Lower revision rates due to malalignment
    • Up to 60% of conventional procedures result in outliers beyond 2° planned alignment

    Source: Multiple peer-reviewed studies

    Better Clinical Outcomes

    • Significantly higher KOOS-JR scores at 6 months (p=0.037)
    • Significantly improved FJS-12 and OKS at 2 years (p≤0.05)
    • Significantly better IKSS-Objective scores (p<0.05)

    Source: Held et al. 2021, Popat et al. 2022

    Faster Recovery

    • 38% sooner hospital discharge (p=0.005)
    • 13% earlier discharge from physiotherapy (p=0.02)
    • >50% faster return to sports activities

    Source: Shearman et al. 2021, Canetti et al. 2018

    Reduced Blood Loss

    • 23.7% less blood loss than conventional surgery (p<0.01)
    • 83% relative risk reduction for blood transfusion
    • Only 2% vs 12% of patients required transfusion

    Source: Khan et al. 2021, Retrospective Analysis

    Lower Revision Rates

    • Significantly lower revision rate (4% vs 11%; p=0.014)
    • 0% revisions due to malalignment with robotic-assisted
    • 99.2% implant survivorship at 2 years

    Source: Mergenthaler et al. 2020, Case Control Study

    Long-Term Results

    Implant Survivorship

    Robotic-assisted surgery demonstrates excellent early survivorship rates, with significantly fewer revisions due to malalignment compared to conventional techniques.

    99.2%

    2-Year Survivorship

    Robotic-assisted UKA

    0%

    Revisions Due to Malalignment

    vs 86% in conventional surgery

    Comparison with Registry Data

    Robotic-Assisted (CORI/NAVIO)99.2%
    New Zealand Registry96.3%
    Swedish Registry96%
    Australian Registry95.7%

    2-year survivorship rates for UKA procedures

    Evidence Base

    Comprehensive Research

    The clinical evidence for Smith+Nephew robotic-assisted surgery spans multiple countries, surgical centers, and peer-reviewed publications.

    30+

    Published Studies

    15

    Accuracy Studies

    13

    Recovery Studies

    RCTs

    Randomized Trials

    Data sourced from Smith+Nephew Evidence Compendium, December 2021, and RI.KNEE Evidence in Focus, August 2023.

    See the Evidence in Action

    Find a hospital in Pakistan equipped with CORI technology and discuss whether robotic-assisted surgery is right for you.

    Find a CORI Hospital